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Newest biopharmaceutical definitions 
Evolving Terminologies for Emerging Technologies
Comments? Questions? Revisions? Mary Chitty 
mchitty@healthtech.com
Last revised July 13, 2010
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21st century Drug discovery & development Map    Informatics map   Technologies map    Biology & chemistry map   Finding guide to terms in these glossaries   Site Map 
** newest of the new definitions

accelerator mass spectrometry: Mass spectrometry

adaptive clinical trials: Drug approvals and clinical trials

Bayesian clinical trials: Drug approvals and clinical trials

biological chemistry: Chemistry (& biology)

biomarker guidelines: Biomarkers 

biomathematics Algorithms

biomedical polymers: Biomaterials

biomolecular screening: Assays & screening

cell specific biomarkers: Biomarkers

cellular dielectric spectroscopy CDS: Technologies

chaperome: -Omes & -omics

Clinical Trial Design Task Force: Clinical Trials

combination therapies:  Drug Discovery & Development

**comparative effectiveness research: Research

comparative systems biology: Genomic Manipulation & Disruption

computational physiology: In Silico & Molecular Modeling

computational sensing: Labels Signaling & detection

**connectome: -Omes & -omics

Copy Number Polymorphisms CNPs: SNPs and Genetic Variations

developability: Drug discovery & development 

diffusion tensor imaging: Molecular imaging

disproportionate drug metabolite: Drug safety, Pharmacovigilance & toxicology

drug metabolism: Pharmacogenomics

e-health: http://en.wikipedia.org/wiki/EHealth 

eSNPs expression SNPs: SNPs and genetic variations

evidence based toxicology: Drug safety, Pharmacovigilance & toxicology

exploratory IND:  Drug approvals

expressomics: -Omes & -omics

follow-on drug: Drug discovery & development 

fragment based drug discovery  Assays and screening

genetic susceptibility: Molecular diagnostics -- genetic & genomic testing

GIS Geographic Information Systems: Molecular Medicine and Diagnostics

**glycomimetics: Glycosciences

green chemistry: Chemistry & biology

GWAS Genome Wide Association Sequencing: Sequencing

**health disparities: Molecular Medicine

human induced pluripotent stem cells hiPS: Stem cells

inflammasome: -Omes & -omics

integrative and organ systems pharmacology: Pharmacogenomics

** in vitro adventitious assays: Assays & screening   

in vitro diagnostic multivariate index assays IVDMIAs: Genetic & genomic testing

integrative biology: Pharmaceutical biology

kidney safety biomarkers: Biomarkers

label free detection: Labels Signaling & detection

lead hopping: Assays

mass spectrometry" IUPAC Mass Spectrometry Standard definitions of terms relating to mass spectrometry Provisional recommendations, 2006 http://www.iupac.org/reports/provisional/abstract06/murray_prs.pdf  

materials chemistry: Chemistry & biology

medical resequencing: Sequencing

mesoscopic biology: Expression genes & proteins

metabolite: Drug safety, Pharmacovigilance & toxicology

microdosing Pharmacogenomics

microtissues: Cell biology

mitochondriomics: -Omes & -omics

molecular biosensors: Labels Signaling & detection

molecular crowding: Biomolecules

molecular electronics: Nanoscience & miniaturization

molecular events: Cancer diagnostics, genomics, prognostics & therapeutics 

molecular pharmacology Pharmacogenomics

mRNA biomarkers: Biomarkers

nanolabels: Labels Signaling & detection

nanomedicine: Nanoscience & miniaturization 

nanotechnology in the clinical laboratory setting: Molecular Medicine

natural competence: DNA

network pharmacology: Pharmacogenomics

next generation sequencing: Sequencing

niche busters: Drug discovery & development

-Omes & -omics: Lots of new terms including alleome, chromatinomics, chromosonics, cryobionomics, embryogenomics, epitomics, fragonomics, lectinomics, mitogenomics, Nobonomics, paleogenomics, RNome, RNomics, separomics, strainomics, transgenomics

oncolytic: Cancer diagnostics, genomics, prognostics & therapeutics

patient engagement: Molecular Medicine

patient navigation:  Cancer diagnostics, genomics, prognostics & therapeutics

pharmacokinetics: Pharmacogenomics

pharmacological biomarkers: Biomarkers

pharmacologically active metabolite: Drug safety, Pharmacovigilance & toxicology

Phase II clinical trial design: Clinical Trials

Phase zero, Phase O: Drug approvals

physiologically based pharmacodynamics: Pharmacogenomics

pipeline problem:  Drug discovery

post-genomic chemistry: Chemistry & biology

preclinical safety biomarkers: Biomarkers

predictive ADME: Drug safety & pharmacovigilance

predictive biomarkers: Biomarkers

predictive toxicology: Drug safety, toxicology & pharmacovigilance

process chemistry: Chemistry & biology 

Proteomic Standards Initiative: Proteomics

quantitative pharmacology: Pharmacogenomics

REMS Risk
Evaluation and Mitigation Strategy : Drug Safety

resourceome: -Omes & -Omics   

ridiculome: -Omes & -Omics

safety pharmacology: Drug Safety & Pharmacovigilance

selection biomarkers: Biomarkers

semantic systems biology: Genomic & Proteomic Manipulation & Disruption including RNAi 

small molecule biomarkers: Biomarkers

solubility: Chemistry & biology

supramolecular electronics: Nanoscience & miniaturization

systems pharmacology: Pharmacogenomics

scaffold hopping: Chemistry

Sentinel Initiative: Drug safety, toxicology & pharmacovigilance

soft drug design: Molecular modeling

target hopping: Drug targets

therapeutic antibodies: Drug targets

top-down mass spectrometry: Mass spectrometry

translational biomarkers: Biomarkers

translational pharmacodynamics: Pharmacogenomics

type 0, type I, type II biomarkers: Biomarkers

women's health: Molecular Medicine

women's health statistical modeling: Molecular Medicine

Bibliography
Alpha glossary index
How to look for other unfamiliar  terms

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