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Molecular Medicine information sources
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Molecular Medicine Definitions  Overviews and introductions  

Molecular Medicine Bibliographies
Science Online, Medical Resources

Molecular Medicine databases
CGAP Cancer Genome Anatomy Project
, NCBI  An interdisciplinary program established and administered by the National Cancer Institute to generate the information and technological tools needed to decipher the molecular anatomy of the cancer cell.

Cochran Library, Wiley  Evidence based medicine databases

Estonian Genome Project

GeneCards, Weizmann Institute, Israel  Human genes, their products and involvements in diseases,  "hot (frequently requested) genes" 

Marshfield Clinic's Personalized Medicine Research Project

OMIM Online Mendelian Inheritance in Man

UK BioBank, Dept of Health, Medical Research Council, Wellcome Trust  Genes, environment and health

Database directories

Molecular Medicine Journals
See also Journals  Drug discovery & development  Pharmacogenomics   Toxicogenomics

BMC Medical Genetics, BioMedCentral, 2000-   All aspects of medical genetics.

British Medical Journal: Molecular Medicine  

Cancer Epidemiology, Biomarkers and Prevention, AACR  Peer-reviewed research on cancer causation, mechanisms of carcinogenesis, prevention, and survivorship. Topics include descriptive, analytical, biochemical, and molecular epidemiology; the use of biomarkers to study the neoplastic and preneoplastic processes in humans; chemoprevention and other types of prevention trials; and the role of behavioral factors in cancer etiology and prevention.

Journal of Molecular Medicine, Springer Verlag, 1995-,id:100437,1 All aspects of human biology and pathophysiology. The application of research involving gene technology, gene therapy, molecular structural analysis, genetic epidemiology and molecular and clinical pharmacology has made unprecedented progress and precision possible in the understanding, prevention, diagnosis and treatment of human diseases. These areas of molecular medicine, therefore, are given particular attention by the editorial board.

Medscape Medscape, Inc. 1999- 
Medscape: Molecular Medicine

Molecular Cancer Research, AACR, 2002- Focus on the molecular and cellular aspects of cancer. They should present significant new information gathered from basic research that has implications for cancer therapeutics in one of the following areas: Angiogenesis, Metastasis, and the Cellular Microenvironment, Cancer Genes and Genomics, Cell Cycle, Cell Death, and Senescence, DNA Damage and Cellular Stress Responses, Model Organisms, Signaling and Regulation.  Was Cell Growth and Differentiation.

Molecular Genetics and Metabolism, Elsevier, 1998- ...  Investigations that use the tools of biochemistry and molecular biology for studies of normal and diseased states. Research Areas include: Inherited Metabolic Diseases, Biochemical studies of primary enzymatic defects, Molecular genetic analyses of mutations, Pathogenesis of these disorders, including not only primary but also secondary metabolic alterations interactions between cells, Functional roles of and interactions between subcellular compartments and distinct regions within these cellular spaces, termed microcompartments, Metabolic relations between individual enzymes and pathways; Cellular Catalysts, Protein and nonprotein catalysts in normal and deranged cellular metabolism, Relationships between the structure and function of catalytic molecules, Interaction of these catalysts with other cellular components; Disease Pathogenesis, Underlying mechanisms of inherited and acquired diseases, Relationships between genotype and phenotype at the biochemical and molecular levels, Strategies for the metabolic improvement of patients through classical drug and dietary intervention, as well as more novel approaches such as transplantation and gene therapy. Was Biochemical and Molecular Medicine, Biochemical Medicine and Metabolic Biology

Molecular Interventions, ASPET American Society of Pharmacology and Experimental Therapeutics, 2001-  Pharmacological perspectives from biology, chemistry and genomics. 

Nature Genetics

Nature Immunology Nature Publishing, 2000- A multidisciplinary journal in all areas of immunology. Whereas no area is excluded from consideration, priority is given to those studies that provide fundamental insights into the functioning of the immune system. 

Nature Medicine, Nature Publishing, 1995-  Biomedical research encompasses virtually all areas of the life sciences. In its broadest interpretation it includes all biology- based research that aims to understand and improve the human condition. Typically it involves studying fundamental aspects of disease in model systems, be they artificial in vitro systems or in vivo animal models, and then applying the lessons learned to patients. It is a long-term approach. .. The experiments of today, if successful, might yield clinical effects in five to ten years or beyond.  A biomedical research journal devoted to publishing the latest and most exciting advances in biomedical research for scientists and physicians, with an emphasis on clarity of presentation. Articles cover fields such as cancer biology, cardiovascular research, gene therapy, immunology, vaccine development, and neuroscience, aiming to keep Ph.D. and M.D. readers informed of a wide range of biomedical research findings and that explicitly put developments in science into a medical context.  

New England Journal of Medicine, Genomic Medicine series Free full- text access. 

PLOS Medicine, Public Library of Science, launch scheduled mid 2004-

Trends in Molecular Medicine, Elsevier, 2001-    A firm understanding of the molecular basis of disease will lead to new strategies to eliminate it. The academics, clinicians and industrial researchers of the future will need to work together to translate basic scientific discoveries into new therapies, vaccines and diagnostic tests. Aims to catalyse this process: the most important breakthroughs in contemporary biomedical research are presented in a concise, accurate and lively way so that anyone with an interest in tomorrow's medicine can assimilate the information they need. Was Molecular Medicine Today.

See also Journals Drug Discovery and Development  Genomics  Proteomics   Chemical genomics  

Molecular medicine websites
Cancer Handbook, Nature Publishing  IBM Clinical Development

IBM Healthcare and Pharmaceutical

Nanomedicine, NIH Roadmap 

Science KE Knowledge Environment:  Science of Aging  We strive to cover advances on basic mechanisms of aging and age- related diseases rather than purely clinical research. In addition, we endeavor to alert our community to developments in areas that are highly relevant for research on aging, such as new methods for single cell analysis of gene expression and major findings on DNA repair, mitochondrial biology, chromatin modification, protein turnover, somatic mutation, etc.

Molecular Medicine organizations
AMA American Medical Association, Genetics and Molecular Medicine

American Medical Informatics Association

Public Health and genomics 
Public health overview 
Genomics Revolution and Public Health, Univ. of North Carolina Chapel Hill
Why you should care about genetics, quick looks, case studies, resources and links.. 

Public health newsletters
Emerging infectious diseases, CDC, monthly 1996-  Infectious diseases whose incidence in humans has increased in the past 2 decades or threatens to increase in the near future have been defined as "emerging." These diseases, which respect no national boundaries, include: New infections resulting from changes or evolution of existing organisms, Known infections spreading to new geographic areas or populations, Previously unrecognized infections appearing in areas undergoing ecologic transformation, Old infections reemerging as a result of antimicrobial resistance in known agents or breakdowns in public health measures. Recognition of new and reemerging infections and understanding of factors involved in disease emergence, prevention, and elimination. Toward this end, the journal: Investigates factors known to influence emergence: microbial adaptation and change, human demographics and behavior, technology and industry, economic development and land use, international travel and commerce, and the breakdown of public health measures.  

Genomic Impact, Association of State and Territorial Health Officials, monthly

Genomics Weekly Update, CDC  Information about the impact of human genetic research on disease prevention and public health.

Public health websites and directories
CDC Resources/Links  Public health associations, health information associations, standards, vocabularies

Genetics and Public Policy,  Johns Hopkins University    

Public Health and Genomics reports
Khoury, Muin, Wylie Burke and Elizabeth J. Thomson, Genetics and Public Health in the 21st. Century, Centers for Disease Control and Prevention, 1999. and/or Genomic Competencies for the Public Health Workforce, CDC Centers for Disease Control and Prevention, US, 2001

Genetics White Paper, "Our inheritance, our future - realising the potential of genetics in the NHS, Department of Health, UK, 2003  

WHO, Genomics and World Health, 2002 In the coming decades, information generated by genomics will have major benefits for the prevention, diagnosis and management of many diseases which have been difficult or impossible to control. At the same time, this new field presents a series of highly complex scientific, economic, social and ethical issues"

Public Health Genomics Organizations
Centers for Disease Control and Prevention, National Office of Public Health Genomics 

Human Genome Epidemiology Network, CDC

Public Health Genetics, PHGU, UK

Molecular Diagnostics
Molecular Diagnostics Introductions  

Molecular Diagnostics Journals
Diagnostic Molecular Pathology, Lippincott, Williams & Wilkins, 1992-;jsessionid=1fJsyXt02yKP1.... Focuses on new molecular diagnostic techniques with applications for surgical pathology. It publishes original, peer-reviewed contributions on molecular probes for diagnosis, such as tumor suppressor genes, oncogenes, the polymerase chain reaction (PCR), and in situ hybridization. Articles demonstrate how these highly sensitive techniques can be applied for more accurate diagnosis.

Experimental and Molecular Pathology, Elsevier, 1962-  Disease processes in relation to structural and biochemical alterations in mammalian tissues and fluids and on the application of newer techniques of molecular biology to problems of pathology in humans and other animals. The journal also publishes selected interpretive synthesis reviews by bench level investigators working at the "cutting edge" of contemporary research in pathology. Research areas include stem cells, neoangiogenesis, PCR, in situ hybridization, pathobiology of neoplasia, complex infectious diseases, transplantation, cytokines,  flow cytometric analysis, cellular injury

IVD In Vitro Technology For original equipment manufacturers of in vitro diagnostic products. The goal of IVD Technology is to help industry professionals develop, design, and manufacture medical products that comply with complex and demanding regulations and market requirements. Covers Immunodiagnostics, Clinical chemistry products, Hematology products, Microbiology products, Nucleic acid-based probes

Journal of Molecular Diagnostics JMD, American Society of Investigative Diagnostics and Association of Molecular Pathology, 1999-  Scientific advances in the translation and validation of molecular discoveries in medicine into the clinical diagnostic setting, and the description and application of technological advances in the field of molecular diagnostic medicine. The editors welcome for review articles which contain: novel discoveries with direct application to clinical diagnostics or clinicopathologic correlations including studies in oncology, infectious diseases, inherited diseases, predisposition to disease, or the description of polymorphisms linked to disease states or normal variations; the application of diagnostic methodologies in clinical trials; or the development of new or improved molecular methods for diagnosis or monitoring of disease or disease predisposition.

Molecular Diagnostics, Adis, 1996-  Development, application and utilization of molecular diagnostics in patient management. The emphasis is on the identification of biomarkers and the development of molecular diagnostic assays and technologies to improve the treatment of disease.

Molecular Pathology, BMJ Publishing, 1995- Original articles of molecular studies on human material relating to pathogenesis and disease processes. Was Clinical Molecular Pathology,

Molecular Diagnostics Organizations
American Association of Clinical Chemistry
International Federation of Clinical Chemistry 

Association for Molecular Pathology 

National Coalition for Health Professional Education in Genetics NCHPEG  Interdisciplinary coalition of consumer and voluntary groups, government agencies, private industry, managed care organizations, and genetics professional societies

Molecular Diagnostics Directories
GeneTests, Univ of Washington  Gene reviews, laboratory directory, clinic directory, educational materials, glossary. 200+ GeneReviews, 1000+ clinics, 500+ labs, 900+ diseases (clinical and research only).

Molecular Diagnostics Terminology

Other Information resources Genomics, proteomics   Drug discovery & development   Chemical genomics Toxicogenomics Bioinformatics   Cheminformatics     Technologies   Molecular Medicine    Business 

What are genomics and proteomics? chemical genomics?  pharmacogenomics?   toxicogenomics?  What are bioinformatics? cheminformatics?  informatics? 

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